Single Compound Network Toxicology Research Planner

The Problem

Single-compound network-toxicology projects often stop at a list of tools or a summary of papers. The missing piece is an executable study design: how to move from one exposure to compound targets, disease targets, overlap, enrichment, PPI hubs, docking, and optional transcriptomic validation without overclaiming. This skill treats the task as research planning rather than literature review.

How It Works

• Input validation: It expects one compound or exposure, one disease or toxic phenotype, and a validation goal; it redirects clinical diagnosis, individual safety advice, pure wet-lab, or pure epidemiology requests.
• Workload planning: It always produces Lite, Standard, Advanced, and Publication+ configurations, then recommends a primary path.
• Dependency control: Before output, it checks whether compound-target, disease-target, overlap, enrichment, PPI, docking, and transcriptomic claims have declared prerequisites.
• Reference discipline: Formal references should include resolvable identifiers such as DOI, PMID, PMC, or official pages; unverified candidates are marked as evidence gaps.

Boundaries

The skill is aimed at study design, evidence mapping, and reviewer preparation. It does not provide clinical treatment advice or individual exposure-risk judgment, and in public-data-only settings it downgrades experimental-validation and causality claims.