Comparative Network Toxicology Shared Mechanism Research Planner

Problem

Comparing two exposures under one toxic phenotype often produces tool lists or vague reviews instead of an executable design with shared versus specific targets, evidence layers, and validation logic.

How It Works

The skill generates a structured research plan through a fixed workflow:
- Validates inputs such as exposure A + exposure B + shared toxic phenotype + validation emphasis
- Selects patterns for shared/specific mapping, enrichment, PPI, docking, or orthogonal cross-checks
- Outputs Lite / Standard / Advanced / Publication+ workload configs and recommends one primary path
- Builds stepwise workflow, figure plan, minimal executable version, and publication upgrade path
- Adds a reference pack and self-critical risk review, requiring verifiable citations and explicit evidence gaps

Scope Notes

It is for network-toxicology research design, not clinical diagnosis, individual exposure advice, pure wet-lab work, or pure epidemiology. If references or data cannot be verified, it states the gap instead of inventing conclusions.