Tencent IgGM Antibody Design Generative Foundation Model
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About this skill
Problem
When engineers run the IgGM-WDL public WDL app on Tencent Health Omics, they can hit locked AppId mistakes, cross-app calls, duplicate app-name conflicts, local files inaccessible from the runtime container, and ignored trial quotas. This skill narrows the workflow to the single IgGM antibody/nanobody generative foundation model app, keeping AppId and WDL type fixed.
How It Works
The skill drives scripts/omics_cli.py: it checks CLI availability, whoami auth, and config show settings; trial users get quota checks before and after confirmation. It then performs a same-name app check with --type WDL, guiding users to rename a conflicting app instead of deleting or overwriting it. Run mode is public-app form B, with fixed --public-app and --app-type WDL, no --nf-version, and input filled from InputTemplate or overridden by --input. If outdir is present, the result directory is reminded after completion. Local generated files must be confirmed and uploaded to COS with a user-provided --cos-path.
Boundaries
It only serves IgGM-WDL. It does not run other public apps, project-owned apps, or list all platform apps. Out-of-scope requests are rejected, and users should use omics-task-skill. Treat it as a controlled platform-app runner, not a general omics CLI replacement.
Use Cases
- In an existing Tencent Health Omics project, call IgGM-WDL for a given antigen to generate candidate antibody sequences and structures.
- Before importing the public app into a project, check for a duplicate IgGM-WDL name and guide the user to choose a unique name.
- When the run input is a locally generated protein FASTA file, upload it to the bound COS bucket before starting IgGM-WDL.
- After the run finishes or fails asynchronously, remind the user to inspect outdir and preserve stderr for failure triage.
Best For
- Biomedical algorithm engineers who need to run IgGM-WDL for a given antigen and review generated parameters and result paths.
- Omics platform operators who need to verify login, project config, duplicate app names, and COS upload paths before a run.
- Antibody research assistants who need to submit antigen-based generation jobs and check outdir after completion.
- Platform integration developers who need a fixed, single-app runner for IgGM-WDL without exposing other omics apps.
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